Click here to download our free job
search app: iPhone App Android App

Pharmacy News Pharmacy News

Some higher-potency statins linked with diabetes


Taking certain higher-potency statins could put patients at a higher risk of developing diabetes than taking lower-potency statins, a BMJ study indicates (online, 23 May 2013).

Over a 14-year study period, researchers in Canada analysed database records for over 470,000 patients with no history of diabetes who were newly treated with a statin for primary or secondary cardiovascular prevention.

Compared with use of pravastatin (the reference for comparison), use of atorvastatin, simvastatin and rosuvastatin was associated with an increased risk of new-onset diabetes (atorvastatin adjusted hazard ratio 1.22, 95 per cent confidence interval 1.15–1.29; simvastatin 1.10, CI 1.04–1.17; rosuvastatin 1.18, CI 1.10–1.26). Conversely, patients taking fluvastatin and lovastatin were no more likely to develop diabetes than those taking pravastatin.

According to the researchers, the raised risk with rosuvastatin decreased significantly after covariate adjustment and became non-significant once dose was taken into account. They conclude that, compared with pravastatin, treatment with higher-potency statins, especially atorvastatin and simvastatin, might be associated with an increased risk of new-onset diabetes.

However, the researchers acknowledge that they were unable to identify and account for potentially important risk factors for diabetes, such as weight, ethnicity and family history.

The authors of an accompanying editorial write: "These findings may be interpreted to support a true pharmacological class effect of statins on the development of diabetes. However, an alternative explanation — prescribing bias — cannot be ruled out. Patients with an unfavourable risk profile and higher risk of developing diabetes may have been more likely to be prescribed a more potent statin and at a higher dose."


The medicines optimisation revolution gathers pace


Medicines optimisation is a term with which many readers will be familiar. For the past couple of years it has been a well publicised concept used to describe how pharmacists, and other professionals, can improve patient outcomes by helping patients get the most out of their medicines.

Although medicines optimisation is not just an agenda for pharmacy, the profession is ideally placed to lead it and last month the Royal Pharmaceutical Society published guiding principles on medicines optimisation for healthcare professionals (see Box).

Revolutionising patient care

“For once, the pharmacy profession is ahead of the game,” said Keith Ridge, chief pharmaceutical officer for England, at last month’s Guild of Healthcare Pharmacists and United Kingdom Clinical Pharmacy Association annual joint conference (Harrogate, 17–19 May). He was referring to the four RPS medicines optimisation principles, describing them as “simple but robust” with the potential to “revolutionise” medicines use in the NHS. He encouraged pharmacists to adopt the RPS principles and work alongside other professions to ensure patients get the most from the medicines they are prescribed.

“There is an overwhelming desire for quality in healthcare . . . which puts patients’ needs and experience right at its heart,” remarked Dr Ridge. He later added: “With a new health and social care system built on quality, and one which is patient-focused, clinically led and outcome-driven, medicines optimisation has appeared just at the right time.”

So, how is the recently reformed NHS in England now approaching the medicines optimisation agenda, and what support is there to help organisations ensure patients do get real benefits from their medicines and the care they receive?

In the new NHS England commissioning system a dedicated medicines optimisation clinical reference group, led by deputy chief pharmaceutical officer for England Clare Howard, will provide medicines optimisation skills and expertise to specialised medicines commissioning.

The NHS Trust Development Authority is another new NHS organisation that became fully operational in April 2013. It has been charged with overseeing the process of ensuring all NHS trusts reach foundation trust (FT) status — a target set by the Health and Social Care Act 2012 — and has made medicines optimisation one of its key priorities.

Assuring quality

There are around 100 NHS trusts across England — representing a variety of healthcare services including community, mental health and ambulance services, as well as acute care — that are currently pursuing FT status. The NHS TDA will provide support and oversight to these organisations at every stage in the process of becoming an FT, from strategic planning and systems development through to approval for assessment by Monitor, the regulator responsible for granting FT licences.

“The scale of the challenge is quite significant,” said Richard Seal, chief pharmacist at the NHS TDA, speaking at a later session. “We aspire to have sustainable, high-quality services in every part of the NHS.”

Mr Seal likened discharging patients from hospital without considering what happens with their medicines to pushing a patient out the door of an aeroplane without a parachute.

He explained that, in contrast to FT approval processes in the past, quality is sitting alongside finance in the NHS TDA as something that is “extraordinarily important” to obtaining FT status, and this includes quality in the delivery of medicines optimisation and pharmaceutical services.

 

 Medicines optimisation principles

“Medicines optimisation: helping patients to make the most of medicines” has been developed by the Royal Pharmaceutical Society and will serve as good practice guidance for all healthcare providers in England. The four guiding principles (available at www.rpharms.com) are:

  • Aiming to understand the patient’s experience
  • Evidence-based choice of medicines
  • Ensuring medicines use is as safe as possible
  • Making medicines optimisation part of routine practice

Embedding the concepts

Although Mr Seal acknowledges that many NHS trusts already have strong policies and approaches to medicines optimisation, he believes the concepts are not yet embedded in their everyday business — which is something he will be encouraging in his work as clinical lead for medicines optimisation at the NHS TDA.

“Medicines are still the most common therapeutic intervention but, from my perspective, we do not support patients enough to take the medicines they are intended to take,” commented Mr Seal.

With the support of other healthcare bodies, the NHS TDA is in the process of developing a medicines optimisation and pharmaceutical services framework. Expected to be published in the coming months, the framework will be consistent with the RPS principles for medicines optimisation and be used specifically by NHS trusts seeking FT status.

Mr Seal explained that, by using the framework, NHS trusts will be able to establish a baseline of current performance to allow benchmarking of success. It will help identify areas of good practice as well as areas for development, and will provide the NHS TDA with assurance that, when the NHS trusts they have been supporting go forward for assessment by Monitor, they will have robust and effective medicines optimisation systems in place.

 


Admin errors reason for most disallowed NCSO claims


Unsuccessful "no cheaper stock obtainable" (NCSO) claims are mostly due to administrative errors made by contractors, a new Pharmaceutical Services Negotiating Committee survey has discovered. A further 27 per cent are due to errors made by the NHS Business Services Authority (see Panel).

The PSNC said that the current NCSO system urgently needs to be reviewed, adding that it is currently in talks with the Department of Health on the matter.

PSNC head of pricing Harpreet Chana told PJ Online that the PSNC hopes its study and analysis will help contractors to review their endorsement processes and to minimise disallowed claims. "The study also identifies other issues the PSNC is working to resolve with the Department of Health and the NHSBSA. These are the identified errors in claims processing, and the problem with enabling a simple way of making NCSO claims for electronic prescription service prescriptions. We hope to resolve these soon," he said.

Only 40 per cent of eligible items claimed for

The survey examined the impact of the NCSO arrangements using the PSNC’s new electronic auditing system, PRISM. Prescriptions for 14 different products that were granted NCSO concessions and submitted between November 2011 and November 2012 were analysed. In total, the survey encompassed 3,233 items, all of which were eligible for the concessions, from 333 different pharmacies. It found that only 1,284 NCSO claims were made, 39.7 per cent of the claims that could have been submitted.

Of the claims that were submitted, 75.9 per cent were successful, up from 16.3 per cent in a similar survey conducted in 2011. Of the successful claims, 66.5 per cent were paid as endorsed, 16.9 per cent were underpaid and 16.5 per cent were overpaid.

The PSNC suggested that contractors may not be claiming for NCSO items because they have purchased products in short supply at or below the Drug Tariff price or because the prescription was filed away before the NCSO concession was granted. It pointed out that the electronic prescription service is compounding the problem because the electronic claim message cannot be recalled once submitted.

"At present we would advise contractors dispensing electronic prescriptions to either delay submission of the electronic claim message until after the NCSO concessions are announced or make a claim in advance of an announcement being made," said Mrs Chana, who also advised visiting the PSNC website for information on NCSO lines and reading the top tips on endorsement and submission in the May Community Pharmacy News.  

The survey was prompted by the rise in the number of supply issues affecting generic products and the subsequent increase in the number of times pharmacies are claiming for NCSO concessions. In addition, the PSNC said there has been a substantial increase in shortages since November 2012.

Reasons for unsuccessful claims

For claims that were not successful, the following reasons were found:

  1. 31 per cent were missing the supplier, manufacturer or brand name
  2. 29 per cent were missing the pharmacist’s initials
  3. 27 per cent were due to an error made by the NHSBSA
  4. 6 per cent were missing the date
  5. 4 per cent were missing the pack size
  6. 2 per cent were found to not have the NCSO endorsement
  7. 1 per cent were brand or manufacturer prescribed 
 

See also: Reports suggest wholesalers are deliberately inflating prices



Optometry News Optometry News

Essilor signs Polaroid deal

1 January 1970, 12:00 am

Francis Inquiry on GOC agenda

1 January 1970, 12:00 am

BCLA plans £100k brand investment

1 January 1970, 12:00 am


Dentistry News Dentistry News

NHS dentistry shake up 'botched'

24 May 2013, 4:36 pm
The shake-up of the way NHS dentistry services are commissioned has been botched, a Conservative peer – and former dentist – warns

Dogs need teeth brushed, too

24 May 2013, 3:50 pm
Research to support British Dental Health Foundation's National Smile Month reveals 80% of dogs over three will have gum disease


Dentistry News Optometry News Pharmacy News General News

VIDEO: Hopes of India vaccine breakthrough

26 May 2013, 1:57 am
India may be a leading producer and exporter of vaccines, yet the government's immunisation programme fails to reach an estimated 28% of babies born there.

'The cough that paralysed me'

26 May 2013, 1:17 am
'The cough that paralysed me and left me in constant pain'

Vacancy Alerts

Click Here

Quick registration

Click Here

Relocating candidates

Click Here

Overseas candidates

Click Here

Register vacancy

Click Here
Salary and Attitudes Survey 2012
If you refer a friend and they go on to secure a position through us, we will give you £200

CLIENT PARTNERS

  • vchp logo small.png
  • pharmlearn.png
  • whitworth
  • asda
  • lo
  • completeCommunity
  • healthCall
  • scrivens
  • north meols
  • midcounties co operative
  • times 100 logo
  • tomms pharmacy
  • st john care trust.png
  • medic animal.png

FOLLOW US ON:


different approach, better results...

Prospect Health is a market leading specialist in the provision of professional recruitment solutions to healthcare providers across the whole of the UK.

We recruit for the following specialist sectors: Optometry, Pharmacy, Dentistry and Care.

WHAT PEOPLE SAY ABOUT US

I have now been with the new employer for just over 7 weeks and can see myself being still with them in seven years quite happily!

Other agencies that I have dealt with in the past get aggressive if you ever say that you are not interested in a certain vacancy. This was not the case with Prospect.

With respect to the great experience and excellent customer service I received I have subsequently recommended my friends and colleague to prospect.

I felt that the service provided was very personal.

I have been impressed with how much I was kept in touch with and the help I received

I cannot say a big enough "Thank you" to Liam and his team. If you work full time as I do it is so important to enjoy everyday.

I felt that they really listened to what I had to say in terms of the role I was looking for, and treated me with the exactly right mix of friendliness and professiona...

They had my best interests at heart, and every phone call I received from them was as friendly and helpful as possible.

I felt this was very personal service and I really appreciated it. I would definitely recommend Prospect to anyone else I know who is looking for work, and I would gla...

I found prospect to be very professional and a useful agency in securing a new job. I had regular contact with them throughout the whole process and was impressed with...

I am still employed in the position secured through the agency and am very satisfied in this employment.

I would recommend Prospect to others and if I look for other positions in the future I would happily use the agency again

The team at Prospect were very friendly and helpful. They quickly found me a job which suited my hours and location

I was kept fully informed throughout and found the process completed very efficiently

I have not only been amazed by the level of results they have achieved in filling the roles they have been given, but I have also been blown away by the speed they hav...

they have found us some very high calibre candidates in areas where we have struggled to actually find anyone in the past.

I have found everyone who I have dealt with at Prospect to be very professional with a real desire to deliver on promise and understand our needs in full.

I would have no hesitation in recommending Prospect to anyone who is looking to fill pharmacist and pharmacy manager vacancies especially if you are looking for high c...

Prospect stand head and shoulders above the rest on all levels.

I have found them to be extremely knowledgeable of the business we operate in and have a deep understanding of the current pharmacy employment market.

The team at Prospect have a high work ethic together with a tenacity that provides good quality candidates for ‘hard to fill’ gaps.

We can confirm that Prospect are a very valuable resource in providing Assura pharmacy, a range of candidates that we have been unable to access through advertising in...

Prospect have placed a number of candidates with our business in locations including Blackpool, Grimsby, Macclesfield and Edinburgh, all roles where we were struggling...

They have demonstrated a high degree of professionalism in all contact with our business and have a good understanding of what we are looking for.

I would be happy to recommend Prospect to anyone who is struggling to fill pharmacist or technician vacancies or are having problems finding the right calibre of staff...

We know that Prospect will only provide us with suitable candidates and will help facilitate the recruitment process from meetings through to acceptance of an offer.

Many thanks for the splendid service! I would recommend to any employer your professional approach in seeking a person, who will be a key player in their practice/s. ...